Ming-Derg Lai Selected Research

WK175

7/2010

A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity.

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Ming-Derg Lai Research Topics

Disease

65	Neoplasms (Cancer) 01/2024 - 08/2004
9	Breast Neoplasms (Breast Cancer) 01/2023 - 12/2015
9	Neoplasm Metastasis (Metastasis) 01/2023 - 04/2010
9	Carcinogenesis 01/2022 - 10/2007
7	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 10/2004
6	Carcinoma (Carcinomatosis) 01/2023 - 10/2008
6	Infections 10/2021 - 11/2003
6	Stomach Neoplasms (Stomach Cancer) 01/2018 - 10/2011
5	Colonic Neoplasms (Colon Cancer) 01/2024 - 12/2014
5	Urinary Bladder Neoplasms (Bladder Cancer) 09/2023 - 01/2007
4	Lung Neoplasms (Lung Cancer) 11/2019 - 01/2009
4	Adenocarcinoma 10/2017 - 01/2015
4	Liver Neoplasms (Liver Cancer) 12/2015 - 12/2011
3	Colorectal Neoplasms (Colorectal Cancer) 01/2024 - 01/2017
2	Hypoxia (Hypoxemia) 09/2023 - 08/2014
2	Inflammation (Inflammations) 01/2023 - 03/2015
2	Lymphatic Metastasis 01/2023 - 01/2015
2	Melanoma (Melanoma, Malignant) 01/2023 - 02/2017
2	Alzheimer Disease (Alzheimer's Disease) 01/2018 - 02/2015
2	Leukemia 01/2018 - 02/2015
2	Adenocarcinoma of Lung 01/2018 - 01/2016
2	Ovarian Neoplasms (Ovarian Cancer) 11/2016 - 10/2016
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2016 - 01/2014
2	Communicable Diseases (Infectious Diseases) 06/2008 - 03/2008
2	Chronic Hepatitis B 04/2005 - 10/2004
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2023
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2023

Drug/Important Bio-Agent (IBA)

14	Small Interfering RNA (siRNA)IBA 09/2023 - 01/2009
14	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2007
10	Messenger RNA (mRNA)IBA 01/2023 - 11/2004
9	Therapeutic UsesIBA 01/2024 - 08/2004
8	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 11/2003
8	DNA VaccinesIBA 12/2017 - 08/2004
6	Arginine (L-Arginine)FDA Link 01/2023 - 11/2013
5	CytokinesIBA 01/2024 - 08/2004
5	RNA (Ribonucleic Acid)IBA 01/2023 - 02/2018
5	Biomarkers (Surrogate Marker)IBA 01/2020 - 12/2015
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2023 - 11/2013
4	Argininosuccinate Synthase (Argininosuccinate Synthetase)IBA 01/2023 - 11/2013
4	EnzymesIBA 01/2020 - 08/2013
4	Argininosuccinate LyaseIBA 02/2017 - 11/2013
4	Indicators and Reagents (Reagents)IBA 01/2017 - 07/2014
4	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2014 - 01/2009
4	Surface Antigens (Surface Antigen)IBA 06/2010 - 10/2004
3	Oncogene Proteins (Oncogene Protein)IBA 01/2024 - 10/2007
3	ErbB Receptors (EGF Receptor)IBA 10/2021 - 01/2009
3	Complementary DNA (cDNA)IBA 01/2020 - 01/2015
3	Transcription Factors (Transcription Factor)IBA 01/2018 - 02/2015
3	CCAAT-Enhancer-Binding Protein-deltaIBA 01/2018 - 02/2015
3	Cyclin A2IBA 02/2017 - 11/2013
3	VaccinesIBA 06/2008 - 08/2004
2	Neutralizing AntibodiesIBA 01/2024 - 01/2022
2	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 09/2008
2	Valproic Acid (Depakote)FDA LinkGeneric 10/2021 - 10/2011
2	Estrogen ReceptorsIBA 10/2021 - 01/2020
2	Estrogens (Estrogen)FDA Link 10/2021 - 03/2006
2	Histone Deacetylase InhibitorsIBA 01/2021 - 10/2011
2	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2020 - 01/2018
2	Amino Acids FDA Link 01/2020 - 02/2017
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2020 - 11/2003
2	Betulinic AcidIBA 11/2019 - 05/2015
2	ChemokinesIBA 01/2018 - 03/2006
2	Cyclin D1IBA 10/2017 - 09/2008
2	Cyclin DIBA 10/2017 - 03/2016
2	Calcium Channels (Calcium Channel)IBA 08/2017 - 01/2015
2	Cadherins (E-Cadherin)IBA 01/2017 - 04/2010
2	Interleukin-6 (Interleukin 6)IBA 01/2017 - 12/2014
2	Mucin-2IBA 01/2017 - 12/2014
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2017 - 04/2015
2	IntegrinsIBA 11/2016 - 12/2015
2	OsteopontinIBA 03/2015 - 07/2010
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 08/2014 - 08/2010
2	Phosphotransferases (Kinase)IBA 08/2014 - 07/2008
2	Benzo(a)pyreneIBA 10/2011 - 10/2008
2	Toll-Like Receptor 4IBA 03/2008 - 11/2005
2	Hepatitis B Surface Antigens (HBsAg)FDA Link 10/2005 - 10/2004
2	Membrane Proteins (Integral Membrane Proteins)IBA 04/2005 - 11/2004
1	PTX3 proteinIBA 01/2024
1	Tamoxifen FDA LinkGeneric 01/2024
1	Interleukin-16 (Interleukin 16)IBA 01/2024
1	AntibodiesIBA 01/2024
1	Cisplatin (Platino)FDA LinkGeneric 01/2023
1	Nitric Oxide DonorsIBA 01/2023
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2023
1	Trastuzumab (Herceptin)FDA Link 01/2023
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 01/2023
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2023
1	Ribonuclease P (RNase P)IBA 01/2023
1	norvalineIBA 01/2023
1	ArginaseIBA 01/2023
1	Lactate Dehydrogenase 5IBA 01/2023
1	N- (4- amino- 2- methylquinolin- 6- yl)- 2- (4- ethylphenoxymethyl)benzamideIBA 01/2023
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2023
1	Transfer RNA (tRNA)IBA 01/2023
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2023
1	arginine deiminaseIBA 01/2023

Therapy/Procedure

14	Therapeutics 01/2024 - 01/2007
4	Immunotherapy 09/2023 - 01/2017
2	Drug Therapy (Chemotherapy) 01/2023 - 01/2012
1	Adjuvant Chemotherapy 01/2023